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research group publications collaborations candidacy etudiants unice welcome to nice ! website of the nice institute of chemistry -- organic chemistry internship home page -- new paper in med. sci. the "bioactive molecules" team, thanks to the different groups constituting it, focuses on the synthesis of molecules with antiviral or antitumor properties, as well as biological tools (inhibitors, fluorescent probes, diagnostic tests, etc.) needed to the study of their activity in vitro. the team is also developing new methods of immunoassays for the pharmacological study of drugs used in antiviral therapy, and multifunctional nanocarriers used in particular to improve the transfer of genes (gene therapy) and / or cell therapy. the team ( cnrs website ) is working especially on oriented thematic such as design and implementation of nucleosides analogues and oligonucleotides as therapeutic and biological tools. an important activity is the development of tools to study nucleic acid / protein interactions. our approach is interdisciplinary: the chemistry of biological processes is studied by physical methods (spectroscopy) based on the skills of organic chemistry and biochemistry present in the team. one of the major challenges of the post-genomic era and proteomics concerns the characterization and quantification of protein / nucleic acid interactions. in addition to the fundamental aspects of these studies, they also aim to understand the molecular basis of various diseases and to develop diagnostic methods and high throughput screening. to achieve these goals, we must nevertheless have nucleobases sensitive to environmental changes that disrupt as low as possible interfere with the structure and function of these nucleic acids. in this context we explored to access of new tools based on different approaches to label nucleic acids and in particular in the development of new fluorescent probes. if you want to join us, click on the ' candidacy tab ' to submit your application.. organic chemistry internship they wrote about us: our projects nucleic acids and the development of new tools are the main objectives of our research activities. we introduced a new concept based on the fluorescent probes properties to emit at two different wavelengths for an internal and external labeling of nucleic acids. these tools are able to translate with high sensitivity nucleic acid / protein interactions. this project was supported by an 'anr blanche' (2007-2011). it is part of a collaboration with pr. yves mely ( , - faculty of pharmacy, strasbourg) for the photophysical studies and interaction with proteins, pr. alexander demchenko (palladin institute of biochemistry, kiev) and professor vasyl pivovarenko ( - kiev national taras shevchenko, chemistry faculty) for their expertise in the chemistry of fluorescence probes, and dr. cyril kenfack ( - university of douala) for his contributions to modeling studies and ab initio calculations. our expertise in this field has enabled us to propose these photophysical tools to study different biological processes involving nucleic acid / protein interactions. one of our projects is the study of the dna methylation mechanism which is still unclear. a better understanding of this mechanism at the molecular level is a major issue both from a fundamental point of view for life sciences and medicine for the pharmaceutical industry. this research is supported by the frm (2012-2015) and anr (2012-2015). this project is developed in partnership with the team of pr. yves mely ( , - faculty of pharmacy, strasbourg). another project was initiated in collaboration with pr. olga fedorova ( - novosibirsk state university) who is interested in studying dna repair mechanisms (nobel prize in chemistry 2015). a better understanding of these mechanisms is an important issue for the life sciences and human health. this project is supported by the paca region through an exploratory project (2014-2015). fundings organic chemistry internship top of the page adresse de l' icn faculté des sciences parc valrose 28 avenue valrose f06108 nice cedex 2

Informations Whois

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%%
%% This is the AFNIC Whois server.
%%
%% complete date format : DD/MM/YYYY
%% short date format : DD/MM
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%% Rights restricted by copyright.
%% See https://www.afnic.fr/en/products-and-services/services/whois/whois-special-notice/
%%
%% Use '-h' option to obtain more information about this service.
%%
%% [2600:3c03:0000:0000:f03c:91ff:feae:779d REQUEST] >> unice.fr
%%
%% RL Net [##########] - RL IP [#########.]
%%

domain: unice.fr
status: ACTIVE
hold: NO
holder-c: UDN29-FRNIC
admin-c: MB26940-FRNIC
tech-c: GRST1-FRNIC
tech-c: RM4405-FRNIC
tech-c: NB4573-FRNIC
zone-c: NFC1-FRNIC
nsl-id: NSL5870-FRNIC
registrar: GIP RENATER
Expiry Date: 31/12/2017
created: 01/01/1995
last-update: 31/12/2016
source: FRNIC

ns-list: NSL5870-FRNIC
nserver: taloa.unice.fr [134.59.1.7]
nserver: diamant.unice.fr [134.59.132.2]
nserver: samoa.unice.fr [134.59.100.1]
nserver: dns.inria.fr [193.51.208.13]
source: FRNIC

registrar: GIP RENATER
type: Isp Option 1
address: 23-25 Rue Daviel
address: PARIS
country: FR
phone: +33 1 53 94 20 30
fax-no: +33 1 53 94 20 31
e-mail: domaine@renater.fr
website: http://www.renater.fr
anonymous: NO
registered: 01/01/1998
source: FRNIC

nic-hdl: MB26940-FRNIC
type: PERSON
contact: Martial Bouillin
address: Univ. Nice Sophia Antipolis
address: Dsi
address: 28, avenue de Valrose
address: 06103 Nice
country: FR
phone: +33 4 92 07 67 01
e-mail: martial.bouillin@unice.fr
registrar: GIP RENATER
changed: 15/09/2015 nic@nic.fr
anonymous: NO
obsoleted: NO
source: FRNIC

nic-hdl: GRST1-FRNIC
type: PERSON
contact: Gip Renater Support Technique Dns
address: GIP RENATER
address: 23-25, rue Daviel
address: 75013 Paris
country: FR
phone: +33 1 53 94 20 40
e-mail: support@renater.fr
registrar: GIP RENATER
changed: 21/07/2015 nic@nic.fr
anonymous: NO
obsoleted: NO
source: FRNIC

nic-hdl: UDN29-FRNIC
type: ORGANIZATION
contact: Universite de Nice
address: D.S.I.
address: 28, avenue de Valrose
address: 06103 Nice
country: FR
phone: +33 4 92 07 67 07
fax-no: +33 4 92 07 67 00
e-mail: adm-reseau@unice.fr
registrar: GIP RENATER
changed: 15/09/2015 nic@nic.fr
anonymous: NO
obsoleted: NO
eligstatus: ok
eligsource: REGISTRAR
eligdate: 15/09/2015 14:59:57
source: FRNIC

nic-hdl: RM4405-FRNIC
type: PERSON
contact: Richard Manas
address: Universite de Nice - Sophia Antipolis
address: Dsi
address: 28, avenue de Valrose
address: 06103 Nice
country: FR
phone: +33 4 92 07 67 07
fax-no: +33 4 92 07 67 00
e-mail: richard.manas@unice.fr
registrar: GIP RENATER
changed: 17/02/2012 nic@nic.fr
anonymous: NO
obsoleted: NO
source: FRNIC

nic-hdl: NB4573-FRNIC
type: PERSON
contact: Nicolas Bonicco
address: Univ. de Nice Sophia Antipolis
address: Dsi
address: 28, avenue de Valrose
address: 06103 Nice
country: FR
phone: +33 4 92 07 67 07
fax-no: +33 4 92 07 67 00
e-mail: nicolas.bonicco@unice.fr
registrar: GIP RENATER
changed: 17/02/2012 nic@nic.fr
anonymous: NO
obsoleted: NO
source: FRNIC


  REFERRER http://www.nic.fr

  REGISTRAR AFNIC

SERVERS

  SERVER fr.whois-servers.net

  ARGS unice.fr

  PORT 43

  TYPE domain
RegrInfo
DISCLAIMER
%
% This is the AFNIC Whois server.
%
% complete date format : DD/MM/YYYY
% short date format : DD/MM
% version : FRNIC-2.5
%
% Rights restricted by copyright.
% See https://www.afnic.fr/en/products-and-services/services/whois/whois-special-notice/
%
% Use '-h' option to obtain more information about this service.
%
% [2600:3c03:0000:0000:f03c:91ff:feae:779d REQUEST] >> unice.fr
%
% RL Net [##########] - RL IP [#########.]
%

  REGISTERED yes

ADMIN

  HANDLE MB26940-FRNIC

  TYPE PERSON

  CONTACT Martial Bouillin

ADDRESS
Univ. Nice Sophia Antipolis
Dsi
28, avenue de Valrose
06103 Nice

  COUNTRY FR

  PHONE +33 4 92 07 67 01

  EMAIL martial.bouillin@unice.fr

  SPONSOR GIP RENATER

  CHANGED 2015-09-15

  ANONYMOUS NO

  OBSOLETED NO

  SOURCE FRNIC

TECH

  HANDLE NB4573-FRNIC

  TYPE PERSON

  CONTACT Nicolas Bonicco

ADDRESS
Univ. de Nice Sophia Antipolis
Dsi
28, avenue de Valrose
06103 Nice

  COUNTRY FR

  PHONE +33 4 92 07 67 07

  FAX +33 4 92 07 67 00

  EMAIL nicolas.bonicco@unice.fr

  SPONSOR GIP RENATER

  CHANGED 2012-02-17

  ANONYMOUS NO

  OBSOLETED NO

  SOURCE FRNIC

OWNER

  HANDLE UDN29-FRNIC

  TYPE ORGANIZATION

  CONTACT Universite de Nice

ADDRESS
D.S.I.
28, avenue de Valrose
06103 Nice

  COUNTRY FR

  PHONE +33 4 92 07 67 07

  FAX +33 4 92 07 67 00

  EMAIL adm-reseau@unice.fr

  SPONSOR GIP RENATER

  CHANGED 2015-09-15

  ANONYMOUS NO

  OBSOLETED NO

  ELIGSTATUS ok

  ELIGSOURCE REGISTRAR

  ELIGDATE 15/09/2015 14:59:57

  SOURCE FRNIC

DOMAIN

  STATUS ACTIVE

  HOLD NO

  SPONSOR GIP RENATER

  EXPIRY DATE 31/12/2017

  CREATED 1995-01-01

  CHANGED 2016-12-31

  SOURCE FRNIC

  HANDLE NSL5870-FRNIC

NSERVER

  TALOA.UNICE.FR 134.59.1.7

  DIAMANT.UNICE.FR 134.59.132.2

  SAMOA.UNICE.FR 134.59.100.1

  DNS.INRIA.FR 193.51.208.13

  NAME unice.fr

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